
Vitamin D3 — also known as cholecalciferol — is a form of vitamin D. This fat-soluble vitamin is a vital nutrient that the body needs to help keep bones and teeth healthy and strong. It also helps with the absorption of calcium, phosphorous, and other minerals, as well as playing a role in the immune system. Your body produces vitamin D3 naturally when exposed to sunlight. It is also naturally present in or added to some foods and is available as a dietary supplement.
It's important to make sure you get enough vitamin D to maintain good overall health. However, many people don't often get enough of this essential nutrient in their diet, leading to vitamin D deficiency. Vitamin D deficiency can contribute to a host of health problems that overlap with other conditions, making it difficult for you to know if you're deficient.
With Cue, you can purchase an at-home vitamin D test online and get fast, accurate results through the Cue Health App. We also offer various over-the-counter dosages of Vitamin D3 supplements to help treat your Vitamin D deficiency and, if needed, you can chat with a clinician on-demand about what dosage may be right for you.
• Free shipping and discreet home delivery
• HSA/FSA eligible
*Image is for illustrative purposes only; product appearance may vary.
Vitamin D3
Vitamin D3 — also known as cholecalciferol — is a form of vitamin D. Vitamin D3 supplements can help you prevent or treat vitamin D deficiency and related conditions. With Cue, you get fast shipping, discreet home delivery, and on-demand telehealth.
What is Vitamin D3?
Vitamin D3 — also known as cholecalciferol — is a form of vitamin D. This fat-soluble vitamin is a vital nutrient that the body needs to help keep bones and teeth healthy and strong. It also helps with the absorption of calcium, phosphorous, and other minerals, as well as playing a role in the immune system. Your body produces vitamin D3 naturally when exposed to sunlight. It is also naturally present in or added to some foods and is available as a dietary supplement.
It's important to make sure you get enough vitamin D to maintain good overall health. However, many people don't often get enough of this essential nutrient in their diet, leading to vitamin D deficiency. Vitamin D deficiency can contribute to a host of health problems that overlap with other conditions, making it difficult for you to know if you're deficient.
With Cue, you can purchase an at-home vitamin D test online and get fast, accurate results through the Cue Health App. We also offer various over-the-counter dosages of Vitamin D3 supplements to help treat your Vitamin D deficiency and, if needed, you can chat with a clinician on-demand about what dosage may be right for you.
• Free shipping and discreet home delivery
• HSA/FSA eligible
*Image is for illustrative purposes only; product appearance may vary.
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About this treatment
What it's for
Vitamin D3 supplements can help you prevent or treat vitamin D deficiency and related conditions. Vitamin D deficiency is a condition that occurs when you don't get enough vitamin D from sunlight or in your diet. Common symptoms of vitamin D deficiency include fatigue, muscle weakness, aches, or cramps, bone pain, and depression. Vitamin D deficiency can lead to loss of bone density, which can contribute to fractures, osteomalacia, and osteoporosis in adults and rickets in children. It's not easy to find out if you have vitamin D deficiency or to understand how much vitamin D3 you should take. That's why Cue is here to help. We make it easy with at-home tests and on-demand access to healthcare experts who can answer your questions. And, if you need supplements, we deliver them right to your door.
What it does
Vitamin D3 supplements are one of the best ways to raise your blood levels of vitamin D. You can use them when you don't get enough vitamin D through sun exposure or food. They help maintain bone health and are also commonly used with calcium to prevent or treat bone diseases such as osteomalacia, rickets, and osteoporosis.
How to take it
Before taking vitamin D3 at strengths above 4000 IU, be sure to consult with a clinician. A one- to three-month course of higher-dose vitamin D3 may be prescribed when rapid correction of your vitamin D deficiency is clinically indicated. After that, you continue with a maintenance-level dose of the vitamin. Consulting with a clinician will ensure you remedy any deficiency without taking too much vitamin D3, which can lead to toxicity.
Read the information packet that comes with your supplement for specific instructions on how to take vitamin D3. Generally, take your dosage with a meal in the morning or up to several hours before bed. Taking your vitamin D3 supplement with a meal helps your body absorb it much better than taking it on an empty stomach.
Dosages for vitamin D3 vary by age but generally range from 600 to 800 IU per day for adults.¹ Daily upper limit from all sources (food, beverages, and supplements) for adults, including pregnant and breastfeeding women, is 4,000 IU.²
If you have a vitamin D deficiency, your clinician may recommend a higher dose of supplements for a period of time. You can easily speak to a clinician with Cue to discuss your recommended dosage. Cue makes Vitamin D3 available in 100-count bottles at three strengths: 2000 IU, 5000 IU, and 10,000 IU. Based on your vitamin D levels, your clinician will ultimately determine whether you qualify for your prescription and dosage, if applicable. Always speak to your clinician before taking supplements, as taking too much can have adverse health effects.
What you should know
Before taking vitamin D3, tell your healthcare provider about all of your medical conditions, especially if you have or have ever had hyperparathyroidism, a condition in which the body produces too much parathyroid hormone, a natural substance needed to control the amount of calcium in the blood; kidney disease; or high blood levels of calcium.
Tell your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking cholecalciferol (vitamin D3), call your clinician.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Our pharmacists will check the information in your profile to see if this supplement might interact with medications or other supplements you are taking.
Do not take vitamin D3 supplements with any medicine or dietary supplement that contains calcium, phosphorus, or vitamin D unless you have been told to do so by your healthcare professional. The extra calcium, phosphorus, or vitamin D may increase the chance of side effects.
If you take any of the following medications, your healthcare provider may want to change the doses of your medications or monitor you carefully for side effects:
• Orlistat (Xenical and alli) is a weight-loss drug. It can reduce the amount of vitamin D your body absorbs from food and supplements.
• Cholesterol-lowering statins might not work as well if you take high-dose vitamin D supplements. This includes atorvastatin (Lipitor), lovastatin (Altoprev and Mevacor), and simvastatin (FloLipid and Zocor)
• Steroids such as prednisone (Deltasone, Rayos, and Sterapred) can lower your blood levels of vitamin D
• Thiazide diuretics (such as Hygroton, Lozol, and Microzide) could raise your blood calcium level too high if you take vitamin D supplements
Do not take more than the recommended doses of vitamin D3. Common side effects of taking too much vitamin D include nausea, vomiting, muscle weakness, confusion, pain, loss of appetite, dehydration, excessive urination and thirst, and kidney stones. Too much vitamin D can also lead to hypercalcemia — a buildup of calcium in your blood. Extremely high levels of vitamin D can cause kidney failure, irregular heartbeat, and even death.
If you notice any of these symptoms, contact your healthcare provider immediately.
For a full list of side effects, interactions, and contraindications, please visit medlineplus.gov.
What to know about vitamin D deficiency
It's very common
Vitamin D deficiency affects 35% of adults in the United States and almost 50% of people worldwide. An estimated 1 billion people have vitamin D deficiency worldwide.³ Common signs of deficiency include fatigue, muscle weakness, aches, or cramps, bone pain, and depression. A lack of exposure to natural sunlight due to long winters, working indoors, and busy lifestyles can contribute to vitamin D deficiency.
It affects certain people more than others
Vitamin D deficiency can affect anyone who doesn't get enough vitamin D in their diet or through sunlight. However, some children who were breastfed, and people who are older (60 years of age or older), have limited sun exposure, have darker skin, have certain medical conditions that limit fat absorption such as Crohn’s disease or celiac disease, or those who are obese or who have undergone bypass surgery may be at higher risk.
Starting supplementation
Take vitamin D3 supplements with your largest meal of the day. Studies suggest that people who take vitamin D supplements with meals show as much as 50% greater blood levels of vitamin D compared to those who didn’t take their supplements with meals.⁴ With Cue, you can get the tests, supplements, and medications you need to take control of your health, all from the comfort of your home.

What to know about vitamin D deficiency
Frequently asked questions
Are these treatments covered by health insurance?
These treatments are not currently covered by insurance, but we are actively working with health insurance companies to get coverage for Cue Health solutions. However, many medications are FSA/HSA eligible, which means that your health benefits may be able to cover them. We recommend connecting with your insurance provider directly to inquire more about their policies and your plan.
Do I need a prescription?
No, you do not need a prescription to use this treatment. However, please read the 'What you should know' section above and consult with a clinician if you have potential allergies, contraindications, or questions.
Do they expire?
Like most products, these treatments do have a shelf life. Be sure to check the expiration date on your packaging before using your treatment.
Can I return them?
No, this product is nonrefundable.




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¹ https://medlineplus.gov/vitaminddeficiency.html
² https://ods.od.nih.gov/factsheets/VitaminD-Consumer/
³ https://my.clevelandclinic.org/health/diseases/15050-vitamin-d-vitamin-d-deficiency
⁴ https://pubmed.ncbi.nlm.nih.gov/20200983/